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Since environmental toxins often harm the kidneys, I wonder if they play a role in gout. It is my thesis that they do. I have lived in Florida, which is very likely the pesticide capital of the world. I moved away from there because I could not tolerate the constant spraying conducted by my County in the name of mosquito control. The synthetic pyrethrins and the organophosphates they sprayed are known nervous system poisons, and all toxins affect the kidneys.
If the incidence of gout varies between nations, I wonder if the amount of unnatural toxic materials play a role in that disparity. If toxins play a role, I am guessing that the U.S. has the highest gout incidence per capita.
Environmental toxins are covered in a new report: Persistent organic pollutants and hyperuricemia in the U.S. general population. It concludes:
This study is consistent with our hypothesis that the risk of hyperuricemia relates to background exposure to a mixture of POPs even among persons without MetS. There should be further research about whether avoiding exposure to POPs and otherwise decreasing body burden of POPs would be helpful to prevent or manage hyperuricemia or gout.
That sounds to me like there is a link, but we need more research to identify how to manage the problem.
Speaking of links – the abstract is at http://www.ncbi.nlm.nih.gov/pubmed/23958244 with links to the full report. I can’t afford to buy the full report, but if anyone has access to it, I’d appreciate a copy.
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