Allergic to Both Uloric and Allopurinol — any other meds?

[goutguy]

Hi –

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I've had gout for decades; and unfortunately I had severe allergic reactions to both allopurinol and uloric… any suggestions for other medications or ways to reduce uric acid production??? My doctor had me stop taking both immediately, I'd tried them at different times and got swollen lip, hives, other allergy symptom serious side effects.

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thanks…

[Keith Taylor]

Probenecid is an option, but only really effective if you are an under-excreter of uric acid. A 24-hour urine test can check this, and should have already been ordered – or is your doctor out of ideas? Other uricosurics are available, but probenecid appears to be the most effective for gout.

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I have a feint recall of allopurinol de-sensitization, but can't remember how effective this is. Basically, you start on a low, tolerable dose, then increase in tiny increments. Best consult a rheumatologist about that.

[zip2play]

I second probenecid. In the United States it's really all you are left with. I hope you are not allergic to it…a lot of people are.

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Make sure you take urine alkalyzers with it to avoid kidney stones.

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Losartan is uricosuric but only weakly so.

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